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Meet the Team

Our mission-driven team is united by a shared sense of purpose and urgency: to bring a life-changing treatment to CMT1A patients as quickly as possible.

Ari on my shoulders
David Apple | Founder & CEO

Dedication. 

- My 5 yr old son Ari has CMT1A.

- Ari had an earlier onset and has a severe presentation.

- CMT1A is progressive, and is reported to get worse during puberty.

- I have a sense of urgency and will not stop until a treatment is available for Ari.

 

Track-record.  

- I'm a Mech Eng (Johns Hopkins) and an MBA (Imperial College London).

- I was the first go-to-market leader at Notion ($10B) and Typeform ($1B). 

- I advise Sequoia Capital, First Round Capital, and Headline Ventures.

- 3x Founder. Teleconnect (acquired), Apple Sustainability (ran profitably 5 yrs).

 

Perspective.

- I'm energized by solving hard problems. 

- I'm working backwards from the unmet need.

- I'm a Board Member of the CMT Association.

Leadership Team

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Jordan VerPlank, PhD

Chief Scientific Officer (Fractional)

Academic Research Scientist

CMT1A Expert

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Wil Chow

Chief Technology Officer (Fractional)

Program Director in 10 Biotechs

7 IND molecules + 2 NDA drugs

Founding Advisor

Our earliest believer and supporter who gave time, advice, and encouragement before Shark Tooth was anything more than an idea. Simply put, Shark Tooth would not exist without her support.

Cristina Apple Georgoulakis

CMT1A Patient Advocate

Former Partner at 776 Venture Fund

Our Scientific Advisors.

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Artie Suckow, PhD

Former CEO of DTX Pharma

Board of CMTRF

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John Svaren, PhD

U. Wisconsin | Chair CMTA SAB

Co-author Ionis CMT1A paper

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Kim Popovits

CEO Genomic Health

Prev. SVP at Genentech

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Tom Dubensky, PhD

CEO ImmuneSensor

Former CMTA Board Member

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Tim Yu, MD, PhD

Professor Genetics & Genomics

Harvard Medical School

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Davy Chiodin

Chief Development Officer

Day One Bio

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Venkat Reddy

CSO at General Inception

CEO at Enable Medicine

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Phillip Reilly, MD

Co-Founder Luna Genetics

Co-Founder BlueBird Bio

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Gregory Reaman, PhD

Prev. FDA Associate Director

Pediatric Oncology

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Charlotte Sumner, PhD

Professor of Neuroscience

Johns Hopkins Medical School

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Founder Capstan Therapeutics

Adj Professor at U Penn

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Toby Ferguson, MD, PhD

Chief Medical Officer

Voyager Therapeutics

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Steve Scherer, MD, PhD

Professor of Neurology

University of Pennsylvania

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Neil Kumar, PhD

Founder & CEO

BridgeBio

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Salim Dhanji, PhD

Co-Founder & CEO

ME Therapeutics

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Sylvain Gariel

Co-Founder & COO

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Developing treatments for CMT1A, and unlocking solutions for other neuropathies.​

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© 2024 by Shark Tooth Biotech. All rights reserved.

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